Key result
Hypopituitarism in women is linked to higher IL-6 and CRP levels versus healthy controls.
Population
164 women, comprising 53 women with hypopituitarism and 111 healthy control women.
Design
Cross-sectional
Authors
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Elevated IL-6 and CRP may signal excess CV risk in hypopituitarism; leaves open causal role and need for prospective studies.
Cross-Sectional (n=164)
p-value: p=< 0.0001
Women with hypopituitarism exhibit elevated levels of the inflammatory markers CRP and IL-6, suggesting that chronic inflammation may contribute to the increased cardiovascular risk observed in this population.
Sesmilo et al. (2001) conducted a cross-sectional in Hypopituitarism (n=164). Hypopituitarism vs. Healthy control women was evaluated on IL-6 and CRP levels (p=< 0.0001). Hypopituitarism in women was associated with significantly higher levels of the inflammatory markers IL-6 and CRP compared to healthy controls (P < 0.0001).
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