Key result
Inhaled albuterol boosts peak power ~3% and increases fatigue vs placebo in healthy nonasthmatic subjects.
Why the study?
Does acute inhalation of albuterol improve high-intensity power output in healthy nonasthmatic subjects?
Population
15 healthy nonasthmatic subjects (8 male, 7 female, 18-33 yr)
Comparison
Albuterol inhaled 10 minutes prior to exercise vs Placebo inhaled 10 minutes prior to exercise
Design
RCT, Fully randomized, Double blind
Follow-up
Acute (immediate testing)
Authors
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Albuterol may enhance anaerobic power in healthy nonasthmatics; extends RCT evidence for beta-agonist ergogenicity beyond asthma.
RCT (n=15)
Double-blind
Fully randomized
Does acute inhalation of albuterol improve high-intensity power output in healthy nonasthmatic subjects?
Absolute Event Rate: 886.6% vs 858.3%
Acute inhalation of albuterol provides an ergogenic effect on short-term power output in healthy nonasthmatic subjects, independent of its impact on respiratory smooth muscle.
Signorile et al. (1992) conducted an RCT in Healthy nonasthmatic (n=15). Albuterol vs. Placebo was evaluated on Peak power. Acute inhalation of albuterol significantly increased peak power (886.6 W vs 858.3 W) and fatigue (27.2% vs 24.4%) compared to placebo in healthy nonasthmatic subjects.
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