Key result
SVT radiofrequency ablation is linked to a ~241% increase in 3-hour BNP levels.
Why the study?
Does radiofrequency catheter ablation increase plasma B-type natriuretic peptide in patients with paroxysmal supraventricular tachycardia?
Population
36 patients with paroxysmal supraventricular tachycardia undergoing catheter ablation
Comparison
Radiofrequency catheter ablation vs Baseline (pre-ablation levels)
Design
Cohort
Follow-up
24 hours
Authors
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May confound early post-ablation BNP interpretation for heart failure; leaves open prognostic relevance in paroxysmal SVT.
Observational (n=36)
Does radiofrequency catheter ablation increase plasma B-type natriuretic peptide in patients with paroxysmal supraventricular tachycardia?
Absolute Event Rate: 43.54% vs 12.78%
p-value: p=0.0001
Radiofrequency catheter ablation for paroxysmal supraventricular tachycardia transiently increases plasma BNP levels, peaking at 3 hours post-procedure.
Chen et al. (2005) conducted an observational in Paroxysmal supraventricular tachycardia (n=36). Radiofrequency catheter ablation vs. Baseline (pre-ablation) was evaluated on Plasma level of B-type natriuretic peptide (BNP) at 3 hours post-ablation (p=0.0001). Radiofrequency catheter ablation of supraventricular tachycardia significantly increased plasma BNP levels at 3 hours post-procedure compared to baseline (43.54 vs 12.78 pg/mL; P=0.0001).
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