Key result
Rare PPNAD causing ACTH-independent Cushing's syndrome presents without Carney's complex.
Case Report (n=1)
Highlights a rare presentation of primary pigmented nodular adrenocortical disease causing Cushing's syndrome without Carney's complex.
Isolated PPNAD may occur without CNC; leaves open whether current >90% association estimates require revision in ACTH-independent Cushing's.
Primary pigmented nodular adrenocortical disease (PPNAD) is one of the rare cause of adrenocorticotropic hormone (ACTH) independent Cushing's syndrome. More than 90% of the reported PPNAD have been associated with Carney's complex. Primary pigmented nodular adrenocortical disease is one of the major criteria for the diagnosis of Carney's complex (CNC). We report a case of PPNAD which is not associated with CNC. How to cite this article Sadacharan D, Mahadevan S, Ravikumar K, Muthukumar S. Primary Pigmented Nodular Adrenocortical Disease: A Rare Cause of Cushing's Syndrome. World J Endoc Surg 2015;7(1):24-25.
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Mahadevan et al. (2015) conducted a case report in Primary pigmented nodular adrenocortical disease (PPNAD) (n=1). Primary pigmented nodular adrenocortical disease was evaluated. A case of primary pigmented nodular adrenocortical disease (PPNAD), a rare cause of ACTH-independent Cushing's syndrome, was reported without an association with Carney's complex.
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