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By means of a double isotope derivative technique, specific determination of cortisol is obtainable. The present study revealed that the previously demonstrated curve of the 17-hydroxycorticosteroid increase in pregnancy is due to cortisol. It was demonstrated, moreover, that following intrauterine death the maternal cortisol values are low (6 patients). A theory is advanced to explain these results.
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Bro‐Rasmussen et al. (1962) studied this question.
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