Key result
Equivalent electric circuit models successfully simulate heart-lung interactions including valvular incompetence and pulmonary obstruction.
The developed dynamic models of the cardiovascular and respiratory systems can simulate heart-lung interactions and may be useful for model-based controller synthesis in medical devices like ECMO.
A set of linear time‐variant dynamic models for the interactive respiratory/cardiovascular mechanism is constructed and analyzed in this work. By using equivalent electric circuits for heart/blood and lung/air subsystems, the dynamics of cardiovascular subsystem and respiration cycle are established. In order to verify the validity of the dynamic models, numerical simulations and analysis on heart–lung interactions, including the valvular closure incompetence and pulmonary obstruction, are presented and compared with the empirical reports in literature. The derived dynamics of heart–lung interactions can be realized and examined in the biomechanical and medical engineering fields. In addition, the dynamic models can also be used for the model‐based controller synthesis in medical instrumentations, for example, the extracorporeal membrane oxygenation, to retain the function of blood circulation and/or respiration by artificial intelligence.
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Lee et al. (2013) studied Heart-lung interactions (valvular closure incompetence and pulmonary obstruction). Linear time-variant dynamic models using equivalent electric circuits vs. Empirical reports in literature was evaluated on Validity of the dynamic models via numerical simulations. A set of linear time-variant dynamic models using equivalent electric circuits successfully simulated heart-lung interactions, including valvular closure incompetence and pulmonary obstruction.
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