Key result
Pleomorphic liposarcoma shows a ~53% 5-year disease-specific survival rate and frequent relapse in localized disease.
Cohort (n=155)
Pleomorphic liposarcoma is an aggressive sarcoma with a 5-year disease-specific survival of 53% and frequent p53 mutations.
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Warrants margin-negative resection attempts in pleomorphic liposarcoma; leaves open role of adjuvant therapies in recurrent disease.
Ghadimi et al. (2011) conducted a cohort in Pleomorphic liposarcoma (PLS) (n=155). Pleomorphic liposarcoma was evaluated on 5-year disease-specific survival rate. In patients with pleomorphic liposarcoma, the 5-year disease-specific survival rate was 53%, with systemic relapse developing in 35% of patients with localized disease.
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