Key result
Mild and severe depression symptoms predict higher mortality in elderly hemodialysis patients.
Why the study?
The study was conducted to determine if the Geriatric Depression Scale is a predictor of mortality in elderly patients on chronic hemodialysis.
Cohort (n=140)
p-value: p=<0.0001
Depression symptoms flag higher mortality risk in elderly hemodialysis patients; hypothesis-generating for screening and intervention trials.
Introduction The aim of this study was to determine if the Geriatric Depression Scale (GDS) was predictor of mortality in elderly patients on chronic hemodialysis (HD). Methods A total of 140 HD patients ≥65 years were studied. Symptoms of depression were assessed through GDS and cognitive function through the Mini Mental State Examination (MMSE). GDS scores 0–9 are considered normal (Group 1); scores of 10–20 (Group 2) and 21–30 (Group 3) indicate mild and severe depression. Results Median GDS was 13 (11–15): 54 patients in Group 1, 49 in Group 2, and 37 in Group 3. After a follow‐up of 58.85 ± 38.8 months, 94 patients died and 46 were alive. Kaplan–Meier survival was significantly lower in patients of Groups 2 and 3 than in Group 1 (log‐rank χ2: 101.9; DF: 2; p < 0.0001). According to Cox regression analysis, mortality was associated with age and GDS, and inversely associated with MMSE and Kt/V. Conclusion GDS predicts mortality in elderly HD patients.
No takes yet. Share an insight, caveat, or question.
Bossola et al. (2023) conducted a cohort in chronic hemodialysis (n=140). Mild to severe depression (Geriatric Depression Scale score ≥10) vs. Normal Geriatric Depression Scale score (0-9) was evaluated on mortality (p=<0.0001). Mild and severe depression symptoms, assessed by the Geriatric Depression Scale, predicted significantly higher mortality in elderly hemodialysis patients (P<0.0001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: