Key result
Hyperinsulinemia linked to ~199% greater odds of prehypertension.
Why the study?
The association of prehypertension with cardiometabolic and hormonal factors in a population sample was not well determined.
Population
1600 residents of St. Petersburg aged 25-64
Comparison
Optimal BP vs prehypertension vs hypertension
Design
Population-based cross-sectional study
Authors
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Hyperinsulinemia was associated with ~3-fold higher PHTN odds; leaves open whether metabolic screening or insulin-targeted interventions alter hypertension risk.
Cross-Sectional (n=1,591)
Odds Ratio: 2.99 (95% CI 1.22–7.36)
p-value: p=0.017
In a Russian population sample, hyperinsulinemia and insulin resistance were strongly associated with a 2- to 3-fold increased risk of prehypertension.
Ерина et al. (2021) conducted a cross-sectional in Prehypertension (n=1,591). Hyperinsulinemia (insulin >173.0 pmol/L) vs. Insulin ≤173.0 pmol/L was evaluated on Prehypertension (PHTN) (OR 2.99, 95% CI 1.22-7.36, p=0.017). Hyperinsulinemia (insulin >173.0 pmol/L) was significantly associated with increased odds of prehypertension (OR 2.99; 95% CI 1.22-7.36; p=0.017) in a population sample of St. Petersburg residents.
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