What is the clinical evidence from this study?

Study design: Review. Population: Hypertension and Cardiovascular Disease. Intervention: Hypertension vs. Normal blood pressure. Primary outcome: Cardiovascular disease events (HR 1.79, 95% CI 1.46-2.19, p=<0.0001).

What does this research mean for the field?

New-onset hypertension in the Tehran Lipid and Glucose Study population occurred at a crude incidence rate of 33.63 per 1000 person-years over a decade of follow-up, contributing significantly to cardiovascular morbidity and mortality. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

October 20, 2018International Journal of Endocrinology and MetabolismOpen Access

Blood Pressure and Hypertension: Key Findings of the Tehran Lipid and Glucose Study (TLGS)

Q: What are the key findings of this study?

Hypertension was associated with a significantly increased risk of cardiovascular disease (HR 1.79) and all-cause mortality in the Tehran Lipid and Glucose Study population.

Q: What does this research mean for the field?

New-onset hypertension in the Tehran Lipid and Glucose Study population occurred at a crude incidence rate of 33.63 per 1000 person-years over a decade of follow-up, contributing significantly to cardiovascular morbidity and mortality. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Hypertension linked to ~79% higher CVD risk and increased all-cause mortality.

HR 1.79
95% CI 1.46-2.19
P<0.0001

Population

Participants of the Tehran Lipid and Glucose Study, including adults aged ≥ 20 years, adolescents, and…

Design

Review

Follow-up

up to >10 years

Authors

HAHengameh AbdiResearch Institute for Endocrine Sciences AAAtieh AmouzegarResearch Institute for Endocrine Sciences MTMaryam TohidiResearch Institute for Endocrine Sciences

Discussion

Member takes

Implication

Hypertension control remains essential in primary prevention; reinforces established CVD and mortality risks in this longitudinal cohort.

Structured PICO

Population

A review of the Tehran Lipid and Glucose Study cohort summarizing the prevalence, incidence, and cardiovascular impacts of hypertension in Iranian adults followed for over a decade.

Outcome

Incidence of hypertension, prehypertension, cardiovascular disease, stroke, and all-cause mortalityhard clinical

Main Result

Hazard Ratio: 1.79 (95% CI 1.46–2.19)

p-value: p=<0.0001

Findings from the Tehran Lipid and Glucose Study highlight the high prevalence and incidence of hypertension in Iran and its substantial contribution to cardiovascular morbidity and mortality.

Cite This Study

Abdi et al. (2018) conducted a review in Hypertension and Cardiovascular Disease. Hypertension vs. Normal blood pressure was evaluated on Cardiovascular disease events (HR 1.79, 95% CI 1.46-2.19, p=<0.0001). Hypertension was associated with a significantly increased risk of cardiovascular disease (HR 1.79) and all-cause mortality in the Tehran Lipid and Glucose Study population.

synapsesocial.com/papers/6a19232c990f10e0212652c7 https://doi.org/10.5812/ijem.84769

Topics

Hypertension management

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Blood Pressure and Hypertension: Key Findings of the Tehran Lipid and Glucose Study (TLGS)

Discussion

Member takes

Implication

Structured PICO

Main Result

Cite This Study

Topics

Blood Pressure and Hypertension: Key Findings of the Tehran Lipid and Glucose Study (TLGS)

Discussion

Member takes

Implication

Structured PICO

Main Result

Cite This Study

Also Consider

Topics

Also Consider