Key result
Female gender linked to ~23% lower LDL-C control and worse diabetes control vs men.
Why the study?
Are there gender differences in cardiovascular risk factor control and clinical management in hypertensive diabetics with chronic ischemic heart disease?
Cross-Sectional (n=654)
Yes
Are there gender differences in cardiovascular risk factor control and clinical management in hypertensive diabetics with chronic ischemic heart disease?
Absolute Event Rate: 26.6% vs 34.6%
p-value: p=0.04
Diabetic women with hypertension and chronic ischemic heart disease have significantly lower control rates for LDL-cholesterol and diabetes compared to men in clinical practice.
Suggests gender disparities in risk factor control among hypertensive diabetics with IHD; leaves open need for prospective confirmation before guiding practice.
Objective: To determine gender differences in cardiovascular risk factors control and clinical management in hypertensive diabetics with chronic ischemic heart disease.Research design and methods: CINHTIA was a cross-sectional and multicenter survey aimed to evaluate the clinical profile and management of hypertensive outpatients with chronic ischemic heart disease attended by cardiologists in Spanish clinical practice setting.The aim of the present work was to examine the gender differences in the control and treatment of cardiovascular risk factors in the subgroup of patients with diabetes.Adequate blood pressure (BP), LDL-cholesterol and diabetes control rates were defined according to ESH-ESC 2003, NCEP-ATP III and ADA-2005 guidelines, respectively.Results: A total of 654 patients (42.4% women) were included for the present analysis.Women were older.Smoking, sedentary lifestyle and peripheral arterial disease were more frequent in men; left ventricular hypertrophy and heart failure in women.The total number of lipid lowering and antihypertensive agents were similar between genders, but with a trend to use more antidiabetic drugs in women.There was a tendency to a better BP control in men (21.5% vs 17.0%, p=0.09).LDL-cholesterol and diabetes were better controlled in men (34.6% vs 26.6%, p=0.04 and 29.7% vs 22.3%, p=0.025, respectively).Conclusions: Diabetic women with hypertension and chronic ischemic heart disease exhibit lower control rates of cardiovascular risk factors.
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Barrios et al. (2009) conducted a cross-sectional in Hypertension, diabetes, and chronic ischemic heart disease (n=654). Female gender vs. Male gender was evaluated on LDL-cholesterol control (p=0.04). Female gender was associated with significantly lower rates of LDL-cholesterol control (26.6% vs 34.6%, p=0.04) and diabetes control (22.3% vs 29.7%, p=0.025) compared to men.
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