Key result
Male sex linked to ~47% greater blood pressure control and better LDL-C control than women.
Why the study?
Are there sex differences in risk factor control and clinical management among hypertensive outpatients with chronic ischemic heart disease?
Cross-Sectional (n=2,024)
Are there sex differences in risk factor control and clinical management among hypertensive outpatients with chronic ischemic heart disease?
Absolute Event Rate: 44.9% vs 30.5%
p-value: p=<.001
In hypertensive outpatients with chronic ischemic heart disease, women have significantly worse blood pressure and LDL-C control compared to men, highlighting a sex disparity in secondary prevention.
Sex disparities in secondary prevention merit attention; leaves open whether targeted strategies improve control in women with chronic IHD.
Cardiopatía Isquémica Crónica e Hipertensión Arterial en la Práctica Clínica en España (CINHTIA) was a survey designed to assess the clinical management of hypertensive outpatients with chronic ischemic heart disease. Sex differences were examined. Blood pressures (BP) was considered controlled at levels of <140/90 or <130/80 mm Hg in diabetics (European Society of Hypertension/European Society of Cardiology 2003); low-density lipoprotein cholesterol (LDL-C) was considered controlled at levels <100 mg/dL (National Cholesterol Education Program Adult Treatment Panel III). In total, 2024 patients were included in the study. Women were older, with a higher body mass index and an increased prevalence of atrial fibrillation. Dyslipidemia, smoking, sedentary lifestyle, and peripheral arterial disease were more frequent in men. In contrast, diabetes, left ventricular hypertrophy, and heart failure were more common in women. BP and LDL-C control rates, although poor in both groups, were better in men (44.9% vs 30.5%, P<.001 and 33.0% vs 25.0%, P<.001, respectively). Stress testing and coronary angiography were more frequently performed in men.
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Barrios et al. (2008) conducted a cross-sectional in Hypertension and chronic ischemic heart disease (n=2,024). Male sex vs. Female sex was evaluated on Blood pressure control (<140/90 or <130/80 mm Hg in diabetics) (p=<.001). Male sex was associated with significantly better blood pressure control (44.9% vs 30.5%, P<.001) and LDL-C control (33.0% vs 25.0%, P<.001) compared to women.
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