Key result
Carotid plaque and thick CIMT linked to ~123% higher mortality risk in CAD.
Why the study?
Does the presence of carotid plaque and thick CIMT predict cardiac mortality and MACE in patients with coronary artery disease?
Population
1,426 consecutive patients with angiography-proven coronary artery disease (CAD)
Comparison
Presence of carotid plaque and thick carotid… vs Absence of carotid plaque and/or thin CIMT
Design
Cohort
Follow-up
mean 85 months
Authors
Loading...
In patients with CAD, carotid plaque is a stronger prognostic factor than CIMT, and their combination further increases the predictive power for cardiac events.
Cohort (n=1,426)
No
Does the presence of carotid plaque and thick CIMT predict cardiac mortality and MACE in patients with coronary artery disease?
Hazard Ratio: 2.23 (95% CI 1.33–3.76)
Absolute Event Rate: 20.7% vs 3.9%
p-value: p=0.003
In patients with CAD, carotid plaque is a stronger prognostic factor than CIMT, and their combination further increases the predictive power for cardiac events.
Yuk et al. (2015) conducted a cohort in Coronary Artery Disease (n=1,426). Carotid plaque with thick carotid intima-media thickness (CIMT >0.830 mm) vs. Thin CIMT without carotid plaque was evaluated on All-cause mortality (HR 2.23, 95% CI 1.33-3.76, p=0.003). In patients with coronary artery disease, having both carotid plaque and thick intima-media thickness significantly increased mortality risk (HR 2.23) compared to having neither.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: