Hypersensitivity myocarditis confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy
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Key result
Stopping amoxicillin and starting prednisolone resolves hypersensitivity myocarditis on cardiac MRI.
- n=1
Population
A 68-year-old woman presenting with acute chest pain mimicking acute coronary syndromes, with normal…
Design
Case_report
Authors
Discussion
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Implication
May support amoxicillin withdrawal plus steroids in suspected hypersensitivity myocarditis; hypothesis-generating case requiring prospective confirmation.
Study Design
Type
Case Report (n=1)
Multicenter
No
Structured PICO
P
Population
A 68-year-old woman with hypersensitivity myocarditis presenting with acute chest pain mimicking acute coronary syndrome.
I
Intervention
Heart failure management and discontinuation of amoxicillin
O
Outcome
Resolution of hypersensitivity myocarditis
Highlights a rare case of amoxicillin-induced hypersensitivity myocarditis confirmed by CMR and biopsy, which resolved upon drug withdrawal and heart failure therapy.
Limitations
- Endomyocardial biopsy has a risk of sampling error due to the focal nature of myocarditis.
- Endomyocardial biopsy is an aggressive procedure with delayed confirmation of results.
Cite This Study
Park et al. (2014) conducted a case report in Hypersensitivity myocarditis (n=1). Prednisolone and discontinuation of amoxicillin was evaluated on Clinical and imaging resolution of myocarditis. Discontinuation of amoxicillin and administration of prednisolone resulted in complete clinical recovery and resolution of hypersensitivity myocarditis on cardiac magnetic resonance imaging.
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