Key result
True mitral regurgitation affects ~2% of normal children and adolescents, while aortic regurgitation remains rare.
Why the study?
What is the prevalence and characteristics of left-sided valvar regurgitation in normal children and adolescents?
Population
329 normal children and adolescent volunteers (194 male, 135 female, age range 3-18 years)
Design
Cohort
Authors
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Supports defining normal pediatric valvular ranges; leaves open whether trivial MR progresses with age.
Observational (n=329)
No
What is the prevalence and characteristics of left-sided valvar regurgitation in normal children and adolescents?
True mitral regurgitation is rare (<2%) in normal children and adolescents, and aortic regurgitation is very rare, suggesting trivial MR may be related to aging and AR should not be considered a normal finding.
John Thomson (2000) conducted an observational in Normal children and adolescents (n=329). Normal childhood and adolescence was evaluated on Detection of mitral regurgitation with colour flow mapping after valve closure (95% CI 0.38-3.3). True mitral regurgitation was detected in 1.82% (95% CI 0.38-3.3%) of normal children and adolescents, while aortic regurgitation was very rare (0.3%).
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