Key result
MAID chemotherapy stabilizes pleural epithelioid hemangioendothelioma, yielding 10-month survival in a single case.
Case Report (n=1)
This case report describes a rare presentation of pleural epithelioid hemangioendothelioma treated with combination chemotherapy, resulting in disease stabilization and 10-month survival.
May support MAID in rare pleural EHE; hypothesis-generating and requires prospective validation.
Epithelioid hemangioendothelioma (EHE) is a rare tumor of vascular origin. While it can be found in any tissue, it is most often found in lung and liver and usually has an intermediate behavior. EHEs originating from pleural tissue have been less frequently described than those from other sites. Furthermore, to date, all of the cited pleural EHEs were described as highly aggressive. In the present report, we describe a rare case of pleural EHE extending to lung and bone in a 31-year-old woman. The histological diagnosis was confirmed by both conventional examination and immunohistochemistry. Her disease stabilized during the 4th course of adriamycin (45 mg/m(2), day 1-3), dacarbazine (300 mg/m(2), day 1-3) and ifosfamide (2,500 mg/m(2), day 1-3) with mesna, and she survived for 10 months after the diagnosis.
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Lee et al. (2008) conducted a case report in Pleural epithelioid hemangioendothelioma (n=1). MAID chemotherapy regimen was evaluated on Disease response and survival. Treatment with a MAID chemotherapy regimen stabilized disease in a 31-year-old woman with pleural epithelioid hemangioendothelioma, leading to a 10-month survival after diagnosis.
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