What is the clinical evidence from this study?

Study design: Case Report. Population: Deep vein thrombosis (n=2). Intervention: Combined paroxetine and zotepine therapy. Primary outcome: Deep vein thrombosis.

What does this research mean for the field?

Combined therapy with paroxetine and zotepine is associated with the development of acute deep vein thrombosis in patients without conventional risk factors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

May 1, 1997Pharmacopsychiatry

Two Cases of Deep Vein Thrombosis Associated with a Combined Paroxetine and Zotepine Therapy

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Key result

Combined paroxetine and zotepine linked to acute DVT in two patients without common risk factors.

Population

2 patients without common risk factors for venous thrombosis

Design

Case_report

Authors

JPJohannes PantelGoethe University Frankfurt JSJacob N. SchroderDuke University KEK. EysenbachHeidelberg University

Discussion

Member takes

Implication

May signal rare DVT risk with paroxetine-zotepine; case reports leave association and causality open for confirmation.

Study Design

Type

Case Report (n=2)

Structured PICO

Population

Two patients who developed acute deep vein thrombosis after receiving combined therapy with paroxetine and zotepine.

Exposure

Combined therapy with paroxetine and zotepine

Outcome

Acute deep vein thrombosissafety

Combined therapy with paroxetine and zotepine may be associated with the development of deep vein thrombosis, warranting clinical awareness.

Limitations

Clinical observations do not necessarily imply a strict causal relationship between drug administration and thrombosis.
Clinical observations do not necessarily imply a strict causal relationship between drug administration and thrombosis

Cite This Study

Pantel et al. (1997) conducted a case report in Deep vein thrombosis (n=2). Combined paroxetine and zotepine therapy was evaluated on Deep vein thrombosis. Combined therapy with paroxetine and zotepine was associated with the development of acute deep vein thrombosis in two patients without common risk factors for venous thrombosis.

synapsesocial.com/papers/6aa50c693a03b8d03ddc3f6e https://doi.org/10.1055/s-2007-979493

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May 1, 1997Pharmacopsychiatry

Two Cases of Deep Vein Thrombosis Associated with a Combined Paroxetine and Zotepine Therapy

View Full Paper

Ask AI

Bookmark

Key result

Combined paroxetine and zotepine linked to acute DVT in two patients without common risk factors.

Population

2 patients without common risk factors for venous thrombosis

Design

Case_report

Authors

JPJohannes PantelGoethe University Frankfurt JSJacob N. SchroderDuke University KEK. EysenbachHeidelberg University

Discussion

Member takes

Implication

May signal rare DVT risk with paroxetine-zotepine; case reports leave association and causality open for confirmation.

Study Design

Type

Case Report (n=2)

Structured PICO

Population

Two patients who developed acute deep vein thrombosis after receiving combined therapy with paroxetine and zotepine.

Exposure

Combined therapy with paroxetine and zotepine

Outcome

Acute deep vein thrombosissafety

Combined therapy with paroxetine and zotepine may be associated with the development of deep vein thrombosis, warranting clinical awareness.

Limitations

Clinical observations do not necessarily imply a strict causal relationship between drug administration and thrombosis.
Clinical observations do not necessarily imply a strict causal relationship between drug administration and thrombosis

Cite This Study

synapsesocial.com/papers/6aa50c693a03b8d03ddc3f6e https://doi.org/10.1055/s-2007-979493

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