A 23-year-old man with acute lymphoblastic leukemia developed clinical manifestations of acute meningitis, but had only six white blood cells per cubic millimeter in the cerebrospinal fluid (CSF). Herpes simplex virus 1 was isolated from the CSF. The patient died of his leukemia one week later; no morphological abnormalities were found in brain or spinal cord.
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Cappel et al. (1973) studied this question.
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