Key result
FDA warns >3 hours of anesthesia or sedation may impair fetal and early childhood brain development.
Why the study?
Do general anesthetics and sedation medications for >3 hours affect brain development in pregnant women in the third trimester and children younger than 3 years old?
Population
Pregnant women in the third trimester and children younger than 3 years old
Design
Review
Authors
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May warrant caution for prolonged anesthesia in third-trimester pregnancies and children <3; leaves open need for prospective neurodevelopmental trials.
Do general anesthetics and sedation medications for >3 hours affect brain development in pregnant women in the third trimester and children younger than 3 years old?
The FDA warns against using general anesthetics and sedation for >3 hours in third-trimester pregnant women and children under 3 due to potential adverse effects on brain development.
Olutoye et al. (2018) conducted an editorial in Anesthesia exposure during pregnancy and early childhood. General anesthetics and sedation medications (midazolam, propofol, isoflurane, sevoflurane, desflurane) was evaluated on Development of children's brains. The FDA warns that general anesthetics and sedation medications used for >3 hours in third-trimester pregnant women and children under 3 may negatively affect children's brain development.
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