Key result
Genome-based approaches are necessary to determine CVD susceptibility, enable early detection, and guide treatment.
Translating genetic discoveries into clinical practice is essential for preventing cardiovascular disease and reducing mortality.
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May guide personalized CVD prevention; leaves open prospective validation before clinical adoption.
Frazier et al. (2005) conducted a review in Cardiovascular disease. Genomic concepts and genome-based approach was evaluated. A genome-based approach is necessary to determine cardiovascular disease susceptibility, enable early detection, guide treatment response, and establish molecular taxonomy.
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