Cholesterol Reduction and Health Policy: Taking Clinical Science to Patient Care

Editorials1 April 1987Cholesterol Reduction and Health Policy: Taking Clinical Science to Patient CareARNOLD M. EPSTEIN, M.D., M.A., GERRY OSTER, Ph.DARNOLD M. EPSTEIN, M.D., M.A.Search for more papers by this author, GERRY OSTER, Ph.DSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-4-621 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor more than a decade, the relationship between cholesterol and coronary heart disease has been a subject of controversy in the medical community. Whereas numerous epidemiologic studies have documented a consistent, strong, and independent association between cholesterol levels and the incidence of coronary heart disease, evidence that lowering cholesterol levels can reduce coronary risk has been more limited. Hence, although many have been convinced of the clinical value of interventions to reduce cholesterol, others have remained more skeptical of the science informing such efforts. The debate has been intense, in part, because "heart" disease has a special place in the...References1. . The Lipid Research Clinics Coronary Primary Prevention Trial results: I. Reduction in incidence of coronary heart disease. JAMA. 1984;251:351-64. CrossrefMedlineGoogle Scholar2. . The Lipid Research Clinics Coronary Primary Prevention Trial results: II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA. 1984;251:365-74. CrossrefMedlineGoogle Scholar3. National Institutes of Health Consensus Development Conference Statement Lowering blood cholesterol to prevent heart disease. JAMA. 1985;253:2080-6. CrossrefMedlineGoogle Scholar4. GRUNDYBILHEIMERBLACKBURN SDH. Rationale of the diet-heart statement of the American Heart Association: report of nutrition committee. Circulation. 1982;65:839A-54A. MedlineGoogle Scholar5. Recommendations for treatment of hyperlipidemia in adults: a joint statement of the Nutrition Committee and the Council on Arteriosclerosis. Circulation. 1984;69:1067A-90A. MedlineGoogle Scholar6. KRONMAL R. Commentary on the published results of the Lipid Research Clinics Coronary Primary Prevention Trial. JAMA. 1985;253:2091-3. CrossrefMedlineGoogle Scholar7. . Toward a prudent diet for children. Pediatrics. 1983;71:78-80. MedlineGoogle Scholar8. Dietary and pharmacologic therapy for the lipid risk factors. JAMA. 1983;250:1873-9. CrossrefMedlineGoogle Scholar9. KOLATA G. Heart panel's conclusions questioned. Science. 1985;227:40-1. CrossrefMedlineGoogle Scholar10. TAYLORPASSSHEPARDKOMAROFF WTDA. Cholesterol reduction and life expectancy: a model incorporating multiple risk factors. Ann Intern Med. 1987;106:605-14. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPatterns of Physicians’ Treatments for Referral Patients From Public Cholesterol ScreeningMedical Students' Knowledge, Attitudes, and Behavior Concerning Diet and Heart DiseaseEpidemiology and Interaction of Risk Factors in Cardiovascular DiseaseWhy some physicians have concerns about the cholesterol awareness programHealth Outcomes Should be Viewed as an Area under the CurveHypertonie und ErnährungCholesterol Reduction and Life ExpectancyBOB ARNOLD, M.D., LACHLAN FORROW, M.D. 1 April 1987Volume 106, Issue 4Page: 621-623KeywordsCardiovascular therapyCholesterolCoronary heart diseaseEpidemiologyLongitudinal studiesPatientsScience policy Issue Published: 1 April 1987 PDF downloadLoading ...