Key result
Exercise linked to ~89% higher transmitral gradient and elevated PASP in mitral stenosis and prosthetic valves.
Why the study?
Does exercise alter transmitral gradient and pulmonary artery pressure in patients with mitral stenosis or a prosthetic mitral valve as measured by Doppler echocardiography?
Population
23 patients total, comprising 12 patients with mitral stenosis and 11 patients with a prosthetic mitral valve.
Comparison
Exercise with Doppler echocardiographic evaluation vs Rest (baseline measurements prior to exercise)
Design
Cohort
Authors
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Exercise-induced rises in gradients and pressures warrant caution during activity in mitral valve disease; leaves open whether routine testing should guide management.
Observational (n=23)
Does exercise alter transmitral gradient and pulmonary artery pressure in patients with mitral stenosis or a prosthetic mitral valve as measured by Doppler echocardiography?
Exercise Doppler echocardiography is a technically simple and valuable noninvasive method for evaluating hemodynamic changes in patients with mitral valve disease.
Leavitt et al. (1991) conducted an observational in Mitral stenosis or prosthetic mitral valve (n=23). Exercise vs. Rest was evaluated on Changes in transmitral gradient and pulmonary artery pressure. Exercise increased mean transmitral gradient and pulmonary artery systolic pressure in patients with mitral stenosis (from 9 to 17 mm Hg and 41 to 70 mm Hg) and prosthetic mitral valves.
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