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September 12, 2026Implementation Science CommunicationsOpen Access

When is AI “just another innovation”? A comparative conceptual analysis of artificial intelligence and evidence-based practice implementation

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Authors

PNPer NilsénKHKathrine HaldMNMargit Neher

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Overview

Comparative conceptual analysis reveals distinct implementation hurdles for adaptive AI in healthcare, suggesting frameworks require shifts toward lifecycle stewardship.

Key Points

  • To evaluate how various artificial intelligence systems align with or challenge fundamental assumptions of implementation science frameworks, using the Consolidated Framework for Implementation Research (CFIR) as a diagnostic tool.
  • Conducted a comparative conceptual analysis synthesizing foundational implementation science literature, complex intervention and digital health studies, and healthcare AI empirical research.
  • Applied the five core domains of the Consolidated Framework for Implementation Research (CFIR) as an analytical lens to identify areas of alignment and conceptual tension.
  • Static or locked AI tools align well with traditional digital interventions, whereas adaptive, generative, and data-dependent systems present distinct challenges including opacity, probabilistic outputs, performance drift, and vendor-driven updates.
  • Adaptive systems challenge core implementation science assumptions regarding intervention stability, clear boundaries, and evidentiary closure, demonstrating that AI deployment requires ongoing lifecycle stewardship rather than a one-time rollout.

Cite This Study

Nilsén et al. (2026) studied this question.

synapsesocial.com/papers/6aa51f49327956e4761f98eahttps://doi.org/10.1186/s43058-026-01103-w
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