Key result
Preoperative 3-4+ MR is linked to ~20% lower absolute 3-year survival after isolated AVR.
Why the study?
Does isolated aortic valve replacement improve functional mitral regurgitation in patients with concomitant functional MR?
Cohort (n=107)
Does isolated aortic valve replacement improve functional mitral regurgitation in patients with concomitant functional MR?
Absolute Event Rate: 78% vs 98%
p-value: p=0.038
Functional mitral regurgitation does not reliably improve after isolated aortic valve replacement, and moderate-to-severe MR is associated with worse survival, suggesting it should be repaired concomitantly.
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Moderate-to-severe preoperative MR was associated with lower survival after isolated AVR; leaves open whether concomitant repair improves outcomes.
Moazami et al. (2004) conducted a cohort in Functional mitral regurgitation and aortic valve disease (n=107). Preoperative 3 to 4+ functional mitral regurgitation vs. Preoperative 1 to 2+ functional mitral regurgitation was evaluated on Survival at 3 years (p=0.038). In patients undergoing isolated aortic valve replacement, 3-year survival was significantly lower for those with preoperative 3 to 4+ mitral regurgitation compared to 1 to 2+ MR (78% vs 98%, p=0.038).
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