Key result
T2DM is linked to altered clinical and functional features and prognosis in patients with ACS.
Key points are not available for this paper at this time.
Population
Patients with ACS
Comparison
Patients with T2DM vs patients without T2DM
Follow-up
12 months
May signal higher-risk ACS subset with T2DM; leaves open whether diabetes independently worsens 1-year outcomes.
tients without T2DM. Evaluation of patients included general clinical investigations, laboratory tests, coronary angiography, echocardiography, Holter monitoring. Frequency of myocardial revascularization, myocardial infarction and death in 12 months of follow-up was analyzed. Results. Incidence of previous myocardial infarction, stroke, peripheral arterial disease and ob-esity was higher in the group of patients with ACS and T2DM. In patients with T2DM multives-sel coronary artery disease was more common (p=0,001). In the acute period coronary artery bypass grafting was performed more often in patients with T2DM (p=0,03). According to echocar-diography the most common left ventricular myocardial remodeling in patients with T2DM was concentric hypertrophy (p=0,002). According to the results of Holter monitoring heart rate varia-bility was decreased more significant in patients with diabetes. Patients with ACS and T2DM underwent myocardial revascularization more frequently during 12 months of follow-up compared with patients without diabetes (p=0,007). Conclusions. According to our data T2DM increases frequency of myocardial revascularization during 12 months after ACS.
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Е. А. Никитина (2019) studied this question.
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