Key result
Surgical septal-superior RF ablation is associated with ~100% AF freedom despite high pacemaker risk.
Why the study?
Does surgical radiofrequency ablation via septal-superior exposure during mitral valve surgery prevent atrial fibrillation in patients with mitral valve disease?
Observational (n=18)
Does surgical radiofrequency ablation via septal-superior exposure during mitral valve surgery prevent atrial fibrillation in patients with mitral valve disease?
Septal-superior exposure for surgical radiofrequency ablation during mitral valve surgery effectively eliminates atrial fibrillation but is limited as a first-line approach due to a high rate of postoperative pacemaker implantation.
Answers are grounded in this paper and cite their sources.
Pacemaker risk cautions against routine septal-superior ablation in mitral surgery; leaves open efficacy in randomized trials.
BACKGROUND: We review the results of surgical radiofrequency ablation of both atria in patients of mitral valve disease approached by septal-superior exposure and discuss the availability of this approach. METHODS: Eighteen patients with a mean age of 65 years were included in this study. Thirteen patients had mitral valve regurgitation predominantly and five had mitral valve stenosis. Eleven patients underwent mitral valve plasty and valve replacement was carried out in seven. All ablation lesions were created on both atria using radiofrequency energy delivered by a unipolar malleable radiofrequency ablation catheter with seven electrodes at a minimum temperature of 80-85 degrees C for a period of 2 min. RESULTS: At the time of discharge, 14 patients were showed normal sinus rhythm and one patient remained in AF. The other three patients were free from atrial fibrillation; however, they received dual-mode, dual-pacing, dual-sensing pacemaker implantation because of bradycardia during the early postoperative phase. At a mean time of 7 months after surgery, all patients were free from atrial fibrillation; 13 patients showed normal sinus rhythm and five patients received dual-mode, dual-pacing, dual-sensing pacemakers. CONCLUSION: Septal-superior exposure provides an excellent operative view both for mitral valve surgery and for radiofrequency ablation. However, this exposure has not been considered a first-line approach because of the high rate of pacemaker implantation.
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Ishikawa et al. (2007) conducted an observational in Mitral valve disease (n=18). Surgical radiofrequency ablation via septal-superior exposure was evaluated on Freedom from atrial fibrillation at 7 months. Surgical radiofrequency ablation via septal-superior exposure achieved 100% freedom from atrial fibrillation at 7 months, but 27.8% of patients required pacemaker implantation.
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