Key result
Propranolol decreases right-to-left shunting in tetralogy of Fallot.
Why the study?
Does propranolol reduce right-to-left shunting and improve hemodynamics in patients with tetralogy of Fallot?
Population
13 patients with tetralogy of Fallot
Design
Case_series
Authors
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May provide short-term relief in cyanotic tetralogy of Fallot; leaves open long-term utility pending controlled trials.
Does propranolol reduce right-to-left shunting and improve hemodynamics in patients with tetralogy of Fallot?
Propranolol acutely reduces right-to-left shunting and relaxes the right ventricular outflow tract in patients with tetralogy of Fallot, though long-term clinical results have been disappointing.
Cumming et al. (1967) studied Tetralogy of Fallot (n=13). Propranolol was evaluated on Percentage of right-to-left shunting. Propranolol administration decreased the percentage of right-to-left shunting in all 13 patients with tetralogy of Fallot.
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