Key result
Redo mitral valve replacement yields ~81% 10-year survival, though low LVEF and NYHA IV increase mortality.
Why the study?
What are the survival outcomes and risk factors for mortality in patients undergoing redo mitral valve replacement?
Cohort (n=62)
What are the survival outcomes and risk factors for mortality in patients undergoing redo mitral valve replacement?
Redo mitral valve surgery with mechanical prostheses provides encouraging mid-term survival, though outcomes are worse in patients with advanced heart failure symptoms and severe left ventricular dysfunction, suggesting the need for earlier intervention.
May warrant earlier referral in NYHA IV or low-LVEF patients; extends observational data on redo MVR survival.
OBJECTIVE: We aimed to investigate the risk factors for hospital mortality, short (five years) and mid-term (10 years) survival in patients who underwent mitral valve replacements in redo patients with previous mitral valve procedures. PATIENTS AND METHODS: Between September 1989 and December 2003, 62 redo patients have undergone mitral valve replacements due to subsequent mitral valve problems. Preoperative, operative, and postoperative data were analyzed retrospectively and evaluated for risk factors affecting hospital mortality, mid- and long-term survival. RESULTS: The hospital mortality was 6.4%. The one-, five-, and 10-year actuarial survival rates were 94%+/- 2%, 89%+/- 6%, and 81 +/- 9%. New York Heart Association (NYHA) functional class IV, low left ventricular ejection fraction (<35%), increased left ventricular end-diastolic diameter (LVEDD) > 50 mm, female gender, pulmonary edema, and urgent operations were found to be risk factors in short-term survival. NYHA functional class IV, low left ventricular ejection fraction, increased LVEDD, and increased left atrial diameter (LA > 60 mm) were risk factors in mid-term survival. CONCLUSION: Redo mitral valve surgery with mechanical prosthesis offers encouraging short- and mid-term survival. NYHA functional class IV, low left ventricular ejection fraction, and increased left ventricular diameters were especially associated with increased short- and mid-term mortality. Earlier surgical management before the development of severe heart failure and myocardial dysfunction would improve the results of redo mitral valve surgery.
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Akay et al. (2008) conducted a cohort in Previous mitral valve procedures requiring redo mitral valve replacement (n=62). Redo mitral valve replacement was evaluated on Hospital mortality. Redo mitral valve replacement resulted in a hospital mortality of 6.4% and a 10-year survival rate of 81%, with NYHA class IV and low LVEF as key risk factors for mortality.
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