Key result
Redo valvular surgery carries ~6% hospital mortality, strongly associated with hemodialysis and NYHA III/IV.
Why the study?
What are the short- and long-term survival outcomes and predictors of mortality following redo valvular surgery?
Cohort (n=414)
What are the short- and long-term survival outcomes and predictors of mortality following redo valvular surgery?
Redo valvular surgery has an acceptable hospital mortality rate of 5.8%, with early referral recommended to improve outcomes before patients progress to NYHA class III/IV or require hemodialysis.
AIM: We reviewed our experience in redo valvular surgery to evaluate trends in short- and long-term outcomes. METHODS: We reviewed 414 patients (mean age, 62.8 ± 13.6 years) who underwent redo valvular surgery in the past 25 years. A total of 301 patients (54.2%) underwent first-time redo valvular surgeries; 178 (32.1%) were second redos, 60 (10.8%) were third redos, and 16 were fourth redos (2.9%). The mean follow-up period was 6.8 ± 6.3 years. RESULTS: Hospital mortality was 5.8%. New York Heart Association (NYHA) class III/IV (P = 0.0007, odds ratio = 4.403) and hemodialysis (P = 0.0383, odds ratio = 7.196) were risk factors for hospital death. Long-term survival rates at 15 and 20 years were 64.7% ± 4.3% and 59.1% ± 5.0%, respectively. Predictors of late death were first time redo (P = 0.0076, hazard ratio = 0.422) and age younger than 61 years (P = 0.0005, hazard ratio = 0.229). There were significant differences in long-term survival between NYHA classes I/II and III/IV (log-rank test, P = 0.0419) and between the time from redo surgery (log-rank test, P = 0.0189) and age (log-rank test, P = 0.0001). CONCLUSIONS: The hospital mortality rate for redo valve surgery has improved. Early referral for redo surgery can contribute to improving early and late outcomes.
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Fukunaga et al. (2018) conducted a cohort in Redo valvular surgery (n=414). Redo valvular surgery was evaluated on Hospital mortality. Redo valvular surgery had a hospital mortality rate of 5.8%, with NYHA class III/IV (OR 4.403) and hemodialysis (OR 7.196) identified as significant risk factors for hospital death.
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