Key result
Chagas disease coinfection linked to rapid progression and death in two elderly COVID-19 patients.
Why the study?
To describe the first report of patients coinfected with Chagas disease and COVID-19 from hospitalization until death.
Case Report (n=2)
No
Chagas disease may be an important and underrated risk factor for developing severe COVID-19 with poor outcomes, particularly in endemic areas.
American trypanosomiasis, also named Chagas disease (CD), is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi. The disease affects millions of people worldwide, leading yearly to approximately 50,000 deaths. COVID-19, generated by SARS-CoV-2, can lead to lymphopenia and death. We hereby describe the first report of two patients with CD and COVID-19 coinfection, from hospitalization until patients’ death.
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Alberca et al. (2020) conducted a case report in COVID-19 and Chagas Disease coinfection (n=2). COVID-19 and Chagas Disease coinfection was evaluated on Mortality. Two elderly patients coinfected with Chagas disease and COVID-19 experienced rapid disease progression and died, suggesting Chagas disease may be an underrated risk factor for severe COVID-19.
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