Key result
Local anesthesia and sedation for TAVI is linked to shorter anesthesia duration versus general anesthesia.
Why the study?
Does local anesthesia and sedation compared to general anesthesia improve procedural outcomes in symptomatic aortic stenosis patients undergoing transfemoral TAVI?
Cohort (n=151)
No
Does local anesthesia and sedation compared to general anesthesia improve procedural outcomes in symptomatic aortic stenosis patients undergoing transfemoral TAVI?
p-value: p=<0.001
Local anesthesia and sedation for TAVI is associated with shorter anesthesia duration compared to general anesthesia, though with a 16.7% conversion rate and similar ICU stay.
Supports local anesthesia feasibility in TAVI cohorts; leaves open outcome benefits and requires randomized confirmation before practice change.
BACKGROUND/AIM: Transcatheter aortic valve implantation (TAVI) has emerged as a new therapy in aortic stenosis patients with high operative risk. Advances in experiences have shifted the choice of anesthesia from general to local anesthesia and sedation for these patients. We compared our anesthetic experiences in our institute in a period of 2.5 years. MATERIALS AND METHODS: A total of 151 (86 females, 65 males, mean age 76 years) symptomatic aortic stenosis patients undergoing transfemoral TAVI under general anesthesia (GA) (n = 79) and local anesthesia and sedation (LAS) (n = 72) were evaluated retrospectively in regards to anesthetic issues. RESULTS: The mean European System for Cardiac Operative Risk Evaluation (EuroSCORE) values of patients in the GA and LAS groups were 17 and 12, respectively. The anesthesia duration was significantly shorter in the LAS group (P < 0.001) and 16.7% of the patients in the LAS group were switched to general anesthesia. Length of stay in the intensive care unit was similar in the two groups. CONCLUSION: TAVI, applied in high-risk populations, has many challenges for anesthesiologists. With technological advances, it is possible to perform these procedures under sedation with variable advantages. Thus, future studies in regard to anesthesia are required for the success of the procedure and patient safety.
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Kesimci et al. (2016) conducted a cohort in Symptomatic aortic stenosis (n=151). Local anesthesia and sedation vs. General anesthesia was evaluated on Anesthesia duration (p=<0.001). Local anesthesia and sedation for transfemoral TAVI was associated with significantly shorter anesthesia duration compared to general anesthesia (P<0.001), with similar ICU length of stay.
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