Key result
General anaesthesia during TAVI is linked to more AKI, while sedation had all 7 strokes.
Why the study?
The authors aimed to evaluate perioperative anaesthetic experiences and outcomes in patients undergoing TAVI under sedation compared to general anaesthesia.
Does sedation improve outcomes compared to general anaesthesia in patients undergoing TAVI?
Observational (n=159)
Does sedation improve outcomes compared to general anaesthesia in patients undergoing TAVI?
p-value: p=0.028
Local anaesthesia and sedation may be preferable to general anaesthesia for TAVI due to reduced procedure time and acute kidney injury, despite a potential risk of stroke.
GA linked to longer TAVI procedures and AKI; supports sedation preference but leaves open causal benefits pending RCTs.
Objective: Transcatheter aortic valve implantation (TAVI) has emerged as an alternative to surgical aortic valve replacement and has become a popular treatment modality for inoperable or patients at high surgical risk with severe aortic stenosis. We aimed to evaluate our perioperative anaesthetic experiences with patients undergoing TAVI under sedation or general anaesthesia (GA). Methods: One hundred and fifty-nine patients who underwent TAVI procedures were enrolled. Effects on TAVI outcomes of sedation and GA were compared. Results: =0.028) was significantly higher in the GA group. Stroke occurred in seven patients, and all were in the sedation group. Conclusion: GA is related to increased procedure time and acute kidney injury; therefore, local anaesthesia and sedation may be the first option in patients undergoing TAVI.
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İzgi̇ et al. (2023) conducted an observational in Severe aortic stenosis (n=159). Sedation vs. General anaesthesia was evaluated on TAVI outcomes (procedure time, acute kidney injury, stroke) (p=0.028). General anaesthesia during TAVI was associated with increased procedure time and acute kidney injury compared to sedation, while all 7 strokes occurred in the sedation group.
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