Key result
Case report details diagnosis and treatment of highly aggressive congenital EWS/pPNET in a 13-day-old newborn.
Case Report (n=1)
This case report describes the rare occurrence and treatment of congenital Ewing's sarcoma/peripheral primitive neuroectodermal tumor in a newborn.
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Neonatal congenital Ewing sarcoma/PNET warrants inclusion in aggressive mass differentials; extends sparse literature but leaves optimal management open.
Ewing's sarcoma (EWS) and peripheral primitive neuroectodermal tumor (pPNET) are small round cell malignancies that develop in soft tissue and bone. They very rarely affect newborns. A diagnosis of EWS/pPNET depends mainly on immunohistochemistry and molecular/genetic assays. Since these tumors are highly aggressive, patient prognosis is typically very poor, and treatment remains a challenge. Here, we report a 13-day-old newborn diagnosed with congenital EWS/pPNET and describe its treatment.
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Jin et al. (2014) conducted a case report in Congenital Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor (n=1). Treatment for congenital EWS/pPNET was evaluated. A 13-day-old newborn was diagnosed with highly aggressive congenital Ewing's sarcoma/peripheral primitive neuroectodermal tumor and received treatment.
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