Phenformin and Pancreatitis

Letters, Comments, and Corrections1 February 1973Phenformin and PancreatitisALEXANDER A. LEVITAN, M.D., M.P.H.ALEXANDER A. LEVITAN, M.D., M.P.H.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-78-2-306_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The letter by Dr. Wilde (1), which raises the question of a causal association of phenformin and pancreatitis, prompts me to report a case of pancreatitis in association with severe acidosis in a patient on phenformin therapy who, unfortunately, unlike Dr. Wilde's patient, was less than discreet in his consumption of alcohol, thus clouding the causal meaning of the association.The patient was a 68-year-old, well-nourished man who had presumably been eating normally while drinking a pint of whiskey daily and adhering to a therapeutic regimen of phenformin (50 mg daily), tolbutamide (250 mg daily), and an...References1. WILDE H: Pancreatitis and phenformin (letter). Ann Intern Med 77:324, 1972 LinkGoogle Scholar2. BERNIERMILLERSPRINGATE GMC: Lactic acidosis and phenformin hydrochloride. JAMA 184:43-46, 1963 CrossrefMedlineGoogle Scholar1. STRUMSPIRO WH: Chronic pancreatitis. Ann Intern Med 74:264-267, 1971 LinkGoogle Scholar2. BOSSAKJOELSON ER: Acute pancreatitis complicating diabetes mellitus. Arch Intern Med 97:201-207, 1956 CrossrefGoogle Scholar3. FINNCOPE RS: The plasma amylase in diabetic coma. Diabetes 12:141-143, 1963 CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: ALEXANDER A. LEVITAN, M.D., M.P.H.Affiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byA systematic review of acute pancreatitis as an adverse event of type 2 diabetes drugs: from hard facts to a balanced positionDrug-Induced PancreatitisAn increase in creatine kinase secondary to acute pancreatitis: a case reportDrug-induced pancreatitis: A critical reviewEtiology of Acute PancreatitisMetabolic Acidosis and the Use of Buffers in the Critically IIIDRUG-ASSOCIATED PRIMARY ACUTE PANCREATITISLactic acidosis in biguanide-treated diabeticsPhenformin and Hyperamylasemia in Lactic AcidosisLYDIA A. CONLAY, M.D., JOSEPH E. LOEWENSTEIN, M.D., F.A.C.P.Phenformin-Associated PancreatitisHERBERT S. CHASE Jr., M.D., GLEN R. MOGAN, M.D.Lactic acidosis and hyperamylasaemia associated with phenformin therapyCreatine Phosphokinase ElevationCHARLES K. TASHIMA, M.D. 1 February 1973Volume 78, Issue 2Page: 306-308KeywordsAlcohol consumptionEatingPancreatitis ePublished: 1 December 2008 Issue Published: 1 February 1973 PDF downloadLoading ...