Key result
Reduced LVEF post-MI is associated with ~17-point lower KCCQ scores at 2.5 years versus normal LVEF.
Why the study?
Does reduced left ventricular ejection fraction during hospitalization for acute myocardial infarction predict worse health-related quality of life at 2.5 years?
Population
n=256 patients with acute myocardial infarction who responded to the Kansas City Cardiomyopathy…
Comparison
Reduced or intermediate left ventricular… vs Normal LVEF (>50%)
Design
Cohort
Follow-up
2.5 years
Authors
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LVEF reduction post-MI flags higher long-term HRQoL risk; leaves open whether targeted interventions improve outcomes.
Cohort (n=256)
Does reduced left ventricular ejection fraction during hospitalization for acute myocardial infarction predict worse health-related quality of life at 2.5 years?
Absolute Event Rate: 68% vs 85%
p-value: p=<0.001
LVEF measured during hospitalization for acute MI is an independent determinant of health-related quality of life 2.5 years later.
Kvan et al. (2008) conducted a cohort in Acute myocardial infarction (n=256). Reduced (<40%) or intermediate (40%-50%) left ventricular ejection fraction vs. Normal LVEF (>50%) was evaluated on Kansas City Cardiomyopathy Questionnaire (KCCQ) clinical summary score (p=<0.001). Reduced left ventricular ejection fraction (<40%) during hospitalization for MI was associated with lower KCCQ clinical summary scores 2.5 years later compared to normal LVEF (68 vs 85; p<0.001).
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