Key result
Ventricular repolarization parameters during HUTT fail to predict future arrhythmias in children with vasovagal syncope.
Why the study?
Ventricular repolarization parameters measured during the HUTT can indicate electrical instability but are infrequently assessed, prompting evaluation of their potential to indicate future ventricular arrhythmias in children with syncope.
Do ventricular repolarization parameters measured during the head-up tilt test indicate future ventricular arrhythmias in children with vasovagal syncope?
Observational
Do ventricular repolarization parameters measured during the head-up tilt test indicate future ventricular arrhythmias in children with vasovagal syncope?
Children with vasovagal syncope and negative HUTT who exhibit abnormal T-wave refraction and prolonged TpTe duration may require continued cardiological outpatient care.
No significant association observed; leaves open whether tilt-test repolarization parameters predict arrhythmias in pediatric vasovagal syncope.
BACKGROUND: Electrocardiography (ECG) and the head-up tilt test (HUTT) are vital in clinical work-up in children with vasovagal syncope (VVS). Ventricular repolarization parameters (QT) measured during the HUTT can be indicative of electrical instability; however, these parameters are not frequently assessed. This study aimed to investigate if ventricular repolarization parameters measured during the HUTT could be indicative of future ventricular arrhythmias in children with syncope. METHODS: The shape and amplitude of the T-wave and parameters of the repolarization period (QT, QTpeak, Tpeak-Tend) were evaluated in a resting ECG performed on the first day of hospitalization and in ECGs performed during three phases of the HUTT. CONCLUSIONS: We need further follow-up studies to establish the clinical importance of abnormal dynamics of the repolarization period in children with VVS and negative HUTT. Therefore, children with abnormal T-wave refraction and prolonged duration of the TpTe should remain under the care of a cardiological outpatient.
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Kolarczyk et al. (2020) conducted an observational in Vasovagal syncope. Ventricular repolarization parameters during the head-up tilt test was evaluated on Future ventricular arrhythmias (p=0.092). Ventricular repolarization parameters measured during the head-up tilt test in children with vasovagal syncope yielded an unspecified result (P=0.092).
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