Key result
Ventricular repolarization parameters show no correlation with SYNTAX score severity in stable angina.
Why the study?
The relationship between SYNTAX score and cardiac repolarization parameters such as cQTd, Tp-e values, and Tp-e ratios in stable angina pectoris needed evaluation.
Does coronary artery disease severity assessed by SYNTAX score correlate with ventricular repolarization parameters in patients with stable angina pectoris?
Observational (n=160)
No
Does coronary artery disease severity assessed by SYNTAX score correlate with ventricular repolarization parameters in patients with stable angina pectoris?
p-value: p=>0.05
Surface ECG predictors of ventricular arrhythmias do not significantly correlate with SYNTAX score-assessed CAD severity in patients with stable angina pectoris.
No correlation with SYNTAX score; leaves open whether repolarization parameters independently stratify arrhythmic risk in stable angina.
Aim: To examine the relationship between the SYNTAX score (SS) and cardiac repolarization parameters such as cQTd and Tp-e values, and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios in patients who have stable angina pectoris.Methods: 12-lead resting electrocardiograms (ECGs) and SS of 160 patients (51 female and 109 male) undergoing coronary angiography with the pre-diagnosis of stable angina pectoris were evaluated.Patients with a SS below 22 were classified as Group 1 (low-SYNTAX), and those above 22 (high-SYNTAX) as Group 2. Forty-four patients with normal coronary angiography were included in Group 3. Results: Mean age of the patients was 62.4±9.1 years.The heart rate, QRS, QT, cQT and JT durations between the groups were similar.In addition, relatively recent ventricular repolarization indices such as Tp-e interval and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios were also not substantially different between groups.Conclusion: Several surface ECG predictors of ventricular arrhythmias, including QTd, JT and Tp-e intervals and their ratios to QT and JT, are not significantly correlated with SYNTAX score-assessed CAD severity in patients with stable angina pectoris.
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Coşgun et al. (2021) conducted an observational in Stable coronary artery disease (n=160). High SYNTAX score (>22) vs. Low SYNTAX score (<22) and normal coronary anatomy was evaluated on Ventricular repolarization parameters (Tp-e interval, Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios) (p=>0.05). Ventricular repolarization parameters, including Tp-e interval and Tp-e/QT ratio, were not significantly correlated with SYNTAX score-assessed coronary artery disease severity in patients with stable angina pectoris.
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