Key result
ACE DD genotype linked to ~64% higher RVMPI vs II after acute anterior MI.
Why the study?
Does ACE gene polymorphism affect the right ventricular myocardial performance index in patients with a first acute anterior MI?
Cross-Sectional (n=116)
Blinded for echocardiography analysis
No
Does ACE gene polymorphism affect the right ventricular myocardial performance index in patients with a first acute anterior MI?
Absolute Event Rate: 0.59% vs 0.36%
p-value: p=<0.05
The ACE DD genotype is associated with significantly higher right and left ventricular myocardial performance indices following a first acute anterior myocardial infarction.
No takes yet. Share an insight, caveat, or question.
ACE DD genotype may signal greater post-MI RV impairment; hypothesis-generating and should not yet change practice.
Öztürk et al. (2005) conducted a cross-sectional in First acute anterior myocardial infarction (n=116). ACE gene I/D polymorphism (DD genotype) vs. ID and II genotypes was evaluated on Right ventricular myocardial performance index (RVMPI) (p=<0.05). The ACE DD genotype was associated with a significantly higher right ventricular myocardial performance index compared to the II genotype (0.59 vs 0.36, p<0.05) after a first acute anterior myocardial infarction.
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