Key result
Femoro-femoral bypass is linked to an 11.2 mm Hg PCO2 gap increase, reflecting impaired gastric perfusion.
Why the study?
Does distal aortic perfusion with femoro-femoral bypass impair gastric mucosal perfusion in patients undergoing descending aortic surgery?
Observational (n=6)
Does distal aortic perfusion with femoro-femoral bypass impair gastric mucosal perfusion in patients undergoing descending aortic surgery?
Distal perfusion with femoro-femoral bypass during descending aortic surgery impairs gastric mucosal perfusion but may have little effect on postoperative visceral dysfunction.
Answers are grounded in this paper and cite their sources.
May impair gastric mucosal perfusion in descending aortic surgery; hypothesis-generating for effects on visceral outcomes.
The changes in gastric mucosal perfusion during distal aortic perfusion with femoro-femoral bypass (F-F bypass) were assessed by air-automated gastric tonometry. A prospective study was performed in six patients who underwent descending aortic surgery for aortic aneurysm under F-F bypass with mild hypothermia (34 degrees C). Gastric intramucosal pH (pHi) and PaCO2-PgCO2 gap (PCO2 gap) were measured. Data are presented as means and standard deviations and analyzed by using one-way analysis of variance followed by Scheffe test. Perioperative variables of hepatorenal functions are also evaluated. The PCO2 gap significantly increased during F-F bypass (3.0 +/- 2.1 mm Hg at control, 14.2 +/- 5.5 mm Hg during F-F bypass; p = 0.004), indicating abnormal gastric mucosal perfusion during F-F bypass. Significantly low pHi was found at weaning from F-F bypass (7.35 +/- 0.05 at control, 7.21 +/- 0.10 at weaning; p = 0.009), which might be related to progressing systemic metabolic acidosis. No impairment of hepatorenal functions was observed after the surgery. Distal perfusion with F-F bypass during descending aortic surgery could impair the gastric mucosal perfusion, but may have little effect on postoperative visceral dysfunction.
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Tachibana et al. (2006) conducted an observational in Aortic aneurysm (n=6). Femoro-femoral bypass vs. Control (baseline) was evaluated on PaCO2-PgCO2 gap (PCO2 gap) (p=0.004). Distal aortic perfusion with femoro-femoral bypass significantly increased the PCO2 gap (14.2 vs 3.0 mm Hg; p=0.004) and lowered pHi (7.21 vs 7.35; p=0.009), indicating impaired gastric perfusion.
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