Key result
IVC leiomyosarcoma surgery shows ~68% two-year survival despite high postoperative complication rates.
Why the study?
What are the outcomes of surgical treatment in patients with leiomyosarcoma of the inferior vena cava?
Observational (n=21)
No
What are the outcomes of surgical treatment in patients with leiomyosarcoma of the inferior vena cava?
Surgical treatment for leiomyosarcoma of the inferior vena cava is feasible and provides satisfactory 1- and 2-year survival rates despite a 38% complication rate.
Supports surgical resection in select cases; leaves open need for larger series to guide management.
AIM: To evaluate the results of surgical treatment of patients with leiomyosarcoma of inferior vena cava. MATERIAL AND METHODS: For the period 2003-2016 21 patients with leiomyosarcoma of IVC were operated at the abdominal department of Blokhin Russian Cancer Research Center. 23.8% patients (n=5) underwent longitudinal resection of IVC, 23.8% (n=5) - circular resection and ligation of IVC, 23.8% (n=5) - circular resection and ligation of IVC, left renal vein ligation, 9.5% (n=2) - circular resection and replacement of IVC, 9.5% (n=2) - circular resection and replacement of IVC, ligation of left renal vein, 9.5% (n=2) - circular resection and replacement of IVC, left renal vein implantation into the prosthesis. RESULTS: The incidence of postoperative complications was 38% (n=8). Postoperative mortality was 4.8% (n=1). R1-resection was made in 4.8% patients (n=1). 1- and 2-year recurrence-free survival was 67% and 50% respectively. Overall 1- and 2-year survival was 86% and 68% respectively. CONCLUSION: In patients with leiomyosarcoma of inferior vena cava surgery is feasible and safe with satisfactory long-term results.
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Стилиди et al. (2017) conducted an observational in Leiomyosarcoma of inferior vena cava (n=21). Surgical treatment was evaluated on Postoperative complications. Surgical treatment of leiomyosarcoma of the inferior vena cava resulted in a 38% postoperative complication rate, 4.8% mortality, and an overall 2-year survival of 68%.
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