Key result
Frontal QRS-T angle >70° identifies myocardial perfusion defects in patients with prior STEMI.
Why the study?
Frontal QRS-T angle abnormalities reflect electrical instability, but whether the angle predicts myocardial perfusion defects in acute STEMI remained to be evaluated.
Does the frontal QRS-T angle predict myocardial perfusion defects on SPECT in patients with prior STEMI?
Cross-Sectional (n=40)
No
Does the frontal QRS-T angle predict myocardial perfusion defects on SPECT in patients with prior STEMI?
Effect estimate: r = 0.543
p-value: p=<0.001
A frontal QRS-T angle > 70° on a standard ECG can serve as a useful, non-invasive predictor of myocardial perfusion defects in patients with a history of STEMI.
May aid ECG-based identification of perfusion defects post-STEMI; hypothesis-generating and requires prospective validation before adoption.
Background: The frontal QRS-T angle is the angle between ventricular depolarization and repolarization. The QRS-T angle abnormalities will mirror the electrical instability, placing the patient in high risk of cardiac arrhythmia and sudden cardiac death. This study was conducted to analyzed as if the QRS-T angle will predict the myocardial perfusion defect in acute ST elevation myocardial infarction (STEMI). Methods: This is a cross sectional study which conducted in patients with previous history of STEMI in H. Adam Malik General Hospital Medan from June 2018 until March 2020. The patients will then be undergoing electrocardiography (ECG) and myocardial perfusion scintigraphy (SPECT) to acquire the frontal QRS-T angle and myocardial perfusion defect score. Results: Over 40 patients with prior STEMI we found the frontal QRS-T angle has a positive moderate correlation (r = 0,543; p < 0,001) with myocardial perfusion defect. The best cut-off value for frontal QRS-T angle to predict myocardial perfusion defect is > 70o with sensitivity and specificity of 70.6% and 82.6%, respectively. Conclusions: The frontal QRS-T angle is an independent predictor for myocardial perfusion defect in patient with previous history of STEMI.
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Vitri Alya (2021) conducted a cross-sectional in Prior ST elevation myocardial infarction (STEMI) (n=40). Frontal QRS-T angle was evaluated on Myocardial perfusion defect (MPD) score (r = 0.543, p=<0.001). A frontal QRS-T angle >70° predicted myocardial perfusion defects with 70.6% sensitivity and 82.6% specificity (r = 0.543, p < 0.001) in patients with prior STEMI.
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