Key result
Urinary antigen assay and 16S rDNA sequencing of pericardial fluid diagnose culture-negative pneumococcal purulent pericarditis.
Population
1 patient (57-year-old woman) with massive pericardial fluid (purulent pericarditis)
Design
Case_report
Authors
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May facilitate diagnosis of culture-negative purulent pericarditis; leaves open need for prospective validation before wider adoption.
Case Report (n=1)
No
Incorporation of molecular methods such as antigen testing and nucleic acid sequencing can successfully diagnose culture-negative purulent pericarditis.
Nakagawa et al. (2010) conducted a case report in Purulent pericarditis (n=1). Pneumococcal urinary antigen assay and 16S rDNA sequencing was evaluated on Microbiological diagnosis. Pneumococcal urinary antigen assay and 16S rDNA sequencing of pericardial fluid successfully diagnosed culture-negative Streptococcus pneumoniae purulent pericarditis.
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