Key result
Hand-assisted laparoscopy linked to ~25% greater 5-year survival vs conventional laparotomy in colorectal cancer patients ≥80.
Why the study?
Does hand-assisted laparoscopic surgery improve perioperative and survival outcomes in older adult patients (≥80 years) with primary colorectal cancer compared to conventional laparotomy?
Population
102 patients over 80 years old undergoing primary resection for colorectal cancer
Comparison
Hand-assisted laparoscopic surgery (HALS) vs conventional laparotomy (CL)
Design
Single-institution retrospective comparative study
Follow-up
5 years
Authors
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Should not yet change practice in octogenarians; leaves open need for randomized confirmation of survival benefit.
Cohort (n=102)
No
Does hand-assisted laparoscopic surgery improve perioperative and survival outcomes in older adult patients (≥80 years) with primary colorectal cancer compared to conventional laparotomy?
Absolute Event Rate: 73.3% vs 48.2%
p-value: p=0.027
Hand-assisted laparoscopic surgery offers significant advantages over conventional laparotomy, including reduced blood loss, shorter hospital stays, fewer wound infections, and better survival in patients over 80 years old with colorectal cancer.
Koike et al. (2022) conducted a cohort in Primary colorectal cancer (n=102). Hand-assisted laparoscopic surgery (HALS) vs. Conventional laparotomy (CL) was evaluated on 5-year overall survival (p=0.027). Hand-assisted laparoscopic surgery in patients ≥80 years with colorectal cancer was associated with higher 5-year overall survival (73.3% vs 48.2%, P=0.027) compared to conventional laparotomy.
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