Key result
Allograft valves yield excellent long-term aortic outcomes and encouraging early mitral results despite technical challenges.
Why the study?
What is the current status and clinical outcome of using allograft valves for aortic and mitral valve replacement?
What is the current status and clinical outcome of using allograft valves for aortic and mitral valve replacement?
This review highlights the excellent long-term outcomes of allograft aortic valves and the improving early results of allograft mitral valves as technical challenges are overcome.
Excellent aortic allograft durability supports selective use; mitral allografts remain investigational pending prospective trials.
Allograft valves have been used in cardiac valve replacement for 35 years. During much of this time, certain centers have used allograft aortic valves for aortic valve replacement and have reported excellent long-term results. After an initial period of failure using allograft mitral valves for mitral valve replacement, the technical problems of papillary muscle dehiscence and mitral regurgitation appear minimized by current investigators who now report encouraging early results. The current status of allograft use for aortic and mitral valve replacement is reviewed.
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Reardon et al. (1997) conducted a review in Aortic and mitral valve replacement. Allograft valves was evaluated. Allograft valves for aortic valve replacement have shown excellent long-term results, while their use for mitral valve replacement shows encouraging early results despite initial technical problems.
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