Acute Lymphatic Leukemia in a Child of Four Years With a Severe Granulopenic Phase Preceding a Remission

Article1 October 1935ACUTE LYMPHATIC LEUKEMIA IN A CHILD OF FOUR YEARS WITH A SEVERE GRANULOPENIC PHASE PRECEDING A REMISSIONLEWIS B. FLINN, M.D., F.A.C.P.LEWIS B. FLINN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-9-4-458 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe study of blood dyscrasias has led to their division into a large number of groups, diseases and syndromes with a baffling nomenclature. The etiology of very few of these various subdivisions is proved and on this account there is no detailed classification which is generally acceptable. Ultimately perhaps a more definite etiological classification will be possible. The work of Castle1 and his associates on the etiology of the macrocytic anemias has done much to clarify the confusion which existed in this field.Search for the etiological agent in the leukemia group has so far met with less success. Here...References1. CASTLE WB: Etiology of pernicious anemia and related macrocytic anemia, ANN. INT. MED., 1933, vii, 2-5. Google Scholar2. GOTTLIEB R: Myeloid insufficiency, ANN. INT. MED., 1934, vii, 895-902. Google Scholar3. JACKSON H: Some little appreciated aspects of malignant lymphoma, Trans. Am. Clim. and Clin. Assoc., 1932. MedlineGoogle Scholar4. SCHULTZ W: Über eigenartige Halserkrankungen und Defekt des Granulozytensystems, Deutsch. med. Wchnschr., 1922, xlviii, 1495. Google Scholar5. DOAN CA: Neutropenie state—significance and therapeutic rationale, Jr. Am. Med. Assoc., 1932, xcix, 194-202. CrossrefGoogle Scholar6. BURKENS JC: Agranulocytose, gevolgd, door leucaemie, Nederl. Tijdschr. v. Geneesk., 1931, lxxv, 2722; Abstr. Am. Jr. Cancer, 1932, xvi, 499. Google Scholar7. EASTON JH: Acute myelogenous leukemia preceded by agranulocytosis, Lancet, 1930, ii, 1394. CrossrefGoogle Scholar8. POTTER HW: Myelogenous leukemia with an aleukemic stage simulating agranulocytosis; a case report, Va. Med. Month., 1932, lviii, 739-743. Google Scholar9. ROSENTHAL N: Hematological aspects of agranulocytosis and other diseases accompanied by extreme leukopenia, Am. Jr. Clin. Path., 1931, i, 7-32. CrossrefGoogle Scholar10. STRUMIA MM: Personal communication to the author. Reports to be published. Google Scholar11. GIVANSHAPIRO TBB: Agranulocytosis in childhood, Am. Jr. Dis. Child., 1933, xlvi, 550-560. Google Scholar12. JACKSONPARKERRINEHARTTAYLOR HFJFFH: Diseases of lymphoid and myeloid tissues; treatment of malignant neutropenia with pentose nucleotides, Jr. Am. Med. Assoc., 1931, xcvii, 1436-1440. CrossrefGoogle Scholar13. JACKSONPARKERTAYLOR HFFH: Nucleotide therapy, Am. Jr. Med. Sci., 1932, clxxxiv, 297-304. CrossrefGoogle Scholar14. REZNIKOFF P: Nucleotide therapy, Jr. Clin. Invest., 1930, vi, 381-391. CrossrefGoogle Scholar15. CRAVERHAAGENSEN LFCD: A note on the occurrence of herpes-zoster in Hodgkin's disease, lymphosarcoma and the leukemias, Am. Jr. Cancer, 1932, xvi, 502-514. Google Scholar16. MORRISRICHSCHIFFFOULGERFELSON RSMLLJHH: Observations on Addisin in diseases of the blood, ANN. INT. MED., 1933, vi, 1536-1545. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: LEWIS B. FLINN, M.D., F.A.C.P.Affiliations: Wilmington, Delaware*Received for publication June 14, 1935. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Bedeutung der sog. Spontanheilungen und Remissionen f�r die Therapie und Pathogenese der Leukosen und malignen TumorenA study of the natural history of acute leukemia with special reference to the duration of the disease and the occurrence of remissionsBone and Joint Pain in Leukemia, Simulating Acute Rheumatic Fever and Subacute Bacterial Endocarditis 1 October 1935Volume 9, Issue 4Page: 458-469KeywordsAnemiaBloodEtiology ePublished: 1 December 2008 Issue Published: 1 October 1935 PDF downloadLoading ...