What does this research mean for the field?

IEGM-guided and surface ECG-guided interventricular delay optimization yield equivalent improvements in hemodynamic and echocardiographic parameters after cardiac resynchronization therapy, with acute LVEF improvement independently predicting favorable outcomes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 4, 2012EP Europace

Comparison of quick optimization of interventricular delay between simple methods: intracardiac electrogram and surface electrocardiogram after cardiac resynchronization therapy

Q: What is the clinical evidence from this study?

Study design: Other. Population: Heart failure (n=51). Intervention: Intracardiac electrogram (IEGM)-guided VV delay optimization vs. Surface ECG-guided VV delay optimization. Primary outcome: Aortic velocity time integral (AVTI).

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Key result

IEGM- and ECG-guided VV optimization equally improve AVTI, while acute LVEF improvement predicts ~23% better outcomes.

n=51

Why the study?

Does IEGM-guided VV delay optimization improve AVTI compared to surface ECG-guided optimization in heart failure patients receiving CRT?

Population

51 heart failure patients scheduled for cardiac resynchronization therapy implantation, mean age 71 ± 10…

Comparison

Interventricular delay optimization guided by… vs Interventricular delay optimization guided by…

Design

Cohort

Follow-up

acute/immediate

Authors

CCChih‐Jen Cheng JHJing‐Long Huang TWTung-Hsin Wu

Discussion

Member takes

Overview

Either IEGM- or ECG-guided VV optimization may suffice post-CRT; leaves open whether acute LVEF response predicts outcomes.

Structured PICO

Does IEGM-guided VV delay optimization improve AVTI compared to surface ECG-guided optimization in heart failure patients receiving CRT?

Population

51 heart failure patients (mean age 71 years, 33% female) scheduled for cardiac resynchronization therapy implantation.

Intervention

Interventricular (VV) delay optimization guided by intracardiac electrogram (IEGM)

Comparator

Interventricular (VV) delay optimization guided by surface electrocardiogram (ECG)

Outcome

Aortic velocity time integral (AVTI)surrogate

Both intracardiac electrogram and surface ECG are equally effective simple methods for quick optimization of interventricular delay after CRT implantation.

Cite This Study

Cheng et al. (2012) studied Heart failure (n=51). Intracardiac electrogram (IEGM)-guided VV delay optimization vs. Surface ECG-guided VV delay optimization was evaluated on Aortic velocity time integral (AVTI). IEGM-guided and surface ECG-guided VV optimization equally improved AVTI, while immediate acute LVEF improvement independently predicted favourable outcomes (OR 1.23; 95% CI 1.03-1.47; P=0.02).

synapsesocial.com/papers/6aa5bd3c5becb0bc28eec84e https://doi.org/10.1093/europace/eus061

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April 4, 2012EP Europace

Comparison of quick optimization of interventricular delay between simple methods: intracardiac electrogram and surface electrocardiogram after cardiac resynchronization therapy

View Full Paper

Ask AI

Bookmark

Key result

IEGM- and ECG-guided VV optimization equally improve AVTI, while acute LVEF improvement predicts ~23% better outcomes.

n=51

Why the study?

Does IEGM-guided VV delay optimization improve AVTI compared to surface ECG-guided optimization in heart failure patients receiving CRT?

Population

51 heart failure patients scheduled for cardiac resynchronization therapy implantation, mean age 71 ± 10…

Comparison

Interventricular delay optimization guided by… vs Interventricular delay optimization guided by…

Design

Cohort

Follow-up

acute/immediate

Authors

CCChih‐Jen Cheng JHJing‐Long Huang TWTung-Hsin Wu

Discussion

Member takes

Overview

Either IEGM- or ECG-guided VV optimization may suffice post-CRT; leaves open whether acute LVEF response predicts outcomes.

Structured PICO

Does IEGM-guided VV delay optimization improve AVTI compared to surface ECG-guided optimization in heart failure patients receiving CRT?

Population

51 heart failure patients (mean age 71 years, 33% female) scheduled for cardiac resynchronization therapy implantation.

Intervention

Interventricular (VV) delay optimization guided by intracardiac electrogram (IEGM)

Comparator

Interventricular (VV) delay optimization guided by surface electrocardiogram (ECG)

Outcome

Aortic velocity time integral (AVTI)surrogate

Both intracardiac electrogram and surface ECG are equally effective simple methods for quick optimization of interventricular delay after CRT implantation.

Cite This Study

synapsesocial.com/papers/6aa5bd3c5becb0bc28eec84e https://doi.org/10.1093/europace/eus061

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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