Key result
hs-CRP and vulnerable plaque rate yield high diagnostic accuracy for T2DM combined with AMI.
Why the study?
Do carotid artery ultrasound and hs-CRP provide diagnostic value for acute myocardial infarction in patients with type 2 diabetes mellitus?
Observational (n=150)
Do carotid artery ultrasound and hs-CRP provide diagnostic value for acute myocardial infarction in patients with type 2 diabetes mellitus?
hs-CRP and carotid artery ultrasound vulnerable plaque rate demonstrate high sensitivity and specificity for the diagnosis of acute myocardial infarction in patients with type 2 diabetes mellitus.
Answers are grounded in this paper and cite their sources.
hs-CRP may stratify risk in T2DM with AMI; leaves open incremental diagnostic value over standard markers.
Hypersensitive C-reactive protein (hs-CRP) is reported to be significant risk indicators not only for the development of cardiovascular disease, but also for the development or progression of type 2 diabetes. The objective of this study was to analyze the significance of hs-CRP in type 2 diabetes mellitus (T2DM) combined with acute myocardial infarction (AMI).Fifty patients with both T2DM and AMI, 50 patients with T2DM alone, and 50 healthy subjects (control group) were selected.Operating characteristic (ROC) analysis revealed that the sensitivity, specificity, accuracy, and critical value in the diagnosis of T2DM combined with AMI using hs-CRP level were 84.6%, 75.9%, 0.856, and 7.34 mg/L, respectively. For using vulnerable plaque rate, these were 92.7%, 95.3%, 0.923, and 0.52, respectively.hs-CRP play a significant role in the early diagnosis of T2DM combined with AMI.
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Li et al. (2018) conducted an observational in Type 2 diabetes mellitus with acute myocardial infarction (n=150). hs-CRP and carotid artery ultrasound vs. T2DM alone or healthy controls was evaluated on Diagnosis of T2DM combined with AMI. hs-CRP level and vulnerable plaque rate demonstrated high diagnostic accuracy for T2DM combined with AMI, with sensitivities of 84.6% and 92.7% and specificities of 75.9% and 95.3%, respectively.
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