Key result
Monotherapy accounts for ~79% of antihypertensive regimens, with CCBs leading regardless of coexisting T2DM.
Cross-Sectional (n=286)
No
Calcium channel blockers are the most commonly prescribed antihypertensive agents, predominantly as monotherapy, in a South Indian tertiary care setting for patients with or without type 2 diabetes.
CCB monotherapy predominates regardless of diabetes status; leaves open optimal regimens for BP control in similar populations.
Objective: To analyze prescription pattern of antihypertensive drugs in patients with hypertension alone and with coexisting diseases. Methodology: A descriptive cross- sectional study was conducted in outpatient department of tertiary care hospital in south India. A total of 286 prescriptions of patients diagnosed to have hypertension with or without coexisting diseases were collected. Details of prescriptions were entered in the preformed pro forma and analyzed. Result: The study included 138 (48.25%) male and 148 (51.75%) female. Out of 286 hypertensives, 122 (42.66%) patients were having co-existing type 2 diabetes mellitus (T2DM). And remaining 164 patients (57.34%) were only hypertensives. Out of 286 patients, 227 (79.31%) patients were on monotherapy, 49 (17.13%) were on dual therapy and remaining 10 patients were on triple anti-hypertensive drugs. Among 150 antihypertensive drugs that are prescribed for hypertensive patients withT2DM, 57 (38%) were calcium channel blocker (CCB), 40 (26.66%) were angiotensin converting enzyme inhibitors (ACEI), 31 (20.66%) were angiotensin receptor blockers (ARB), 13 (8.66%) were diuretics and remaining 9 (6%) were beta blockers. Similarly, among 206 antihypertensive drugs prescribed for hypertension alone patients, 97 (47%) were CCB, 37 (17.96%) were ACEI, 31 (15%) were ARB, 26 (12.62%) were diuretics and remaining 15 (7.28%) were beta blockers. Conclusion: The study has shown that majority of patients were on monotherapy (79.31%) and calcium channel blockers were commonly prescribed for hypertension in patients with or without type 2 diabetes mellitus followed by ACE inhibitors, ARB and beta blockers.
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Adake et al. (2017) conducted a cross-sectional in Hypertension (n=286). Antihypertensive drugs was evaluated on Prescription pattern of antihypertensive drugs. Among 286 hypertensive patients, 79.31% were on monotherapy, with calcium channel blockers being the most commonly prescribed drug class regardless of coexisting type 2 diabetes mellitus.
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