Key result
A 10-fold increase in urinary albumin-to-creatinine ratio was associated with a 57% increased risk for the composite cardiovascular endpoint (HR 1.57, P<0.001) in nondiabetic patients.
Why the study?
Does urinary albumin excretion below the current definition of microalbuminuria predict cardiovascular mortality and events?
Population
Patients with hypertension and left ventricular hypertrophy and a general population cohort of 40,548…
Design
Editorial
Authors
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Urinary albumin excretion predicts cardiovascular risk at levels below the current threshold for microalbuminuria, suggesting the definition should be lowered.
Does urinary albumin excretion below the current definition of microalbuminuria predict cardiovascular mortality and events?
Hazard Ratio: 1.57
p-value: p=<0.001
Urinary albumin excretion predicts cardiovascular risk at levels below the current threshold for microalbuminuria, suggesting the definition should be lowered.
Karagiannis et al. (2008) conducted an editorial in Hypertension and left ventricular hypertrophy (n=40,548). Increased urinary albumin-to-creatinine ratio (UACR) vs. Lower UACR was evaluated on Composite cardiovascular endpoint (HR 1.57, p=<0.001). A 10-fold increase in urinary albumin-to-creatinine ratio was associated with a 57% increased risk for the composite cardiovascular endpoint (HR 1.57, P<0.001) in nondiabetic patients.
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