Key result
Higher intact PTH levels correlate with greater carotid intima-media thickness in renal transplant recipients.
Why the study?
Does normalization of intact parathyroid hormone (iPTH) levels after renal transplantation correlate with changes in common carotid intima-media thickness?
Population
55 normotensive renal transplant recipients, aged 47 +/- 1.7 years, with stable graft function
Design
Cohort
Follow-up
12 months
Authors
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PTH may contribute to post-transplant vascular changes; leaves open whether normalization improves cardiovascular outcomes.
Cohort (n=55)
Does normalization of intact parathyroid hormone (iPTH) levels after renal transplantation correlate with changes in common carotid intima-media thickness?
p-value: p=<0.01
Normalization of intact parathyroid hormone levels after renal transplantation is associated with a significant reduction in carotid intima-media thickness, suggesting a potential mechanism for reducing cardiovascular risk in patients with end-stage renal failure.
Barbara Suwelack (2001) conducted a cohort in Renal transplant recipients (n=55). Intact parathyroid hormone (iPTH) levels was evaluated on Common carotid intima-media thickness (CC IMT) (p=<0.01). Intact parathyroid hormone levels were positively and independently correlated with common carotid intima-media thickness in renal transplant recipients (P<0.01).
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